Epaphroditus was a messenger sent by the church at Philippi with a gift for the apostle Paul, who was under house arrest in Rome (Phil. 2:25; 4:18). While in Rome Epaphroditus became ill and word of his sickness spread to Philippi. As soon as Epaphroditus was well enough, Paul sent him back home to relieve the church's anxiety and to deliver Pauls letter to the Philippians.

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