Bible passage: Genesis 3:15c
Prophet: Moses*
Written: As early as 1400 BC
Gen. 3:15, in addition to being cited as a prophecy that the Messiah would conquer evil and be a human, born of a woman, Bible commentators often extract a third prophetic detail from this verse, that the Messiah would be injured while conquering evil:
"And I will put enmity between you and the woman, and between your offspring and hers; he will crush your head, and you will strike his heel." (Gen. 3:15, NIV)
This comes from the end of the verse, where it says: "... he will crush your head, and you will strike his heel (Gen. 3:15, NIV)." The "he," as previously explained, refers to the Messiah. And the "your" refers to the serpent (Satan).
So the serpent will strike the Messiah's heel but will suffer a strike the head. While commonly viewed as being a promise that the Messiah would defeat evil, the Messiah will suffer an injury. In literal terms, a serpent is unlikely to survive a head crush from a grown human. And the human would suffer from the snake's bite and venom.
The cornerstone of Christianity is that Jesus suffered to the point of death during the crucifixion. As explained in the New Testament, Jesus had lived a perfect and sinless life. His death paid the price of sin for all who believe in him. In Christianity, Jesus conquered sin, Satan and evil by dying on the cross, by suffering the injuries of being beaten and crucified.
Other prophets, namely Isaiah and Zechariah, prophesied that the Messiah would suffer for the sins of others, adding more details to the framework offered in Gen. 3:15, that a redeemer would endure injury while resolving the issue of sin and evil.
* Note: Moses is not the giver of this prophecy but rather the one who recorded the prophecy when he wrote the book of Genesis. The prophecy was delivered by God to Adam and Eve.